General Information Lungs are situated in the chest (thoracic cavity) They wrap around the heart and major blood vessels going to and from the heart and esophagus The right lung has three sections, or lobes, and the left lung has two The lungs and inner walls of the chest are covered with a thin double membrane called the pleura, normally touching and moving easily during breathing Air is inhaled through the nose into the pharynx (back of the throat), the trachea (windpipe),and finally into the mainstem bronchi The bronchial tubes or bronchi branch into smaller tubes within each lobe and again into bronchioles ending in the alveolar ducts Alveolar ducts lead to tiny thin-walled clusters of sacs called alveoli Average lung has about 300 million alveoli The exchange of oxygen and carbon dioxide takes place in the alveoli where blood capillaries are present Lung cancer is now the leading cause of cancer death for both men and women Accountable for 27% of cancer mortality Majority of patients have extensive disease at the time of diagnosis Occurs most often in the 55 to 65 year age group but in recent decades incidence has increased two-fold in the 40 to 44 year old group and ten-fold in the 60 to 64 year group Lungs are vital organs and cancer tends to spread through blood and lymph nodes Common sites of metastasis are brain, liver, bone and lymph nodes